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Expression of Concern: STAT6 knockdown using multiple siRNA sequences inhibits proliferation and induces apoptosis of human colorectal and breast cancer cell lines

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• The article refers to the STAT6 siRNA sequences as “proprietary” as they are covered by patents owned by SIRNA Ltd., a daughter company of Celixir PLC. The patents cover… Click to show full abstract

• The article refers to the STAT6 siRNA sequences as “proprietary” as they are covered by patents owned by SIRNA Ltd., a daughter company of Celixir PLC. The patents cover Europe, Australia, Canada, New Zealand, US, South Africa, and cover the sequences for any use including development and/or sale of research reagents (EP1725658, AU2005217200, CA2599524, NZ549915, US7,566,700 and ZA2006/07471 which are all national/regional phases of the Walker and Hopkin patent in ref. 22). The authors provided documentation to support these statements regarding ownership of the relevant patents.

Keywords: knockdown using; expression concern; concern stat6; using multiple; stat6 knockdown; sirna sequences

Journal Title: PLoS ONE
Year Published: 2021

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