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Recombinant tissue plasminogen activator (rtPA) remains the only therapeutic agent approved for salvaging the penumbra through reperfusion after acute ischemic stroke (AIS) [1]. It effectively dissolves thrombi within 4.5 h… Click to show full abstract
Recombinant tissue plasminogen activator (rtPA) remains the only therapeutic agent approved for salvaging the penumbra through reperfusion after acute ischemic stroke (AIS) [1]. It effectively dissolves thrombi within 4.5 h after stroke onset, but it increases the risk of cerebral hemorrhage and malignant cerebral edema in AIS patients [2]. Thrombosis and inflammation are highly intertwined contributors to the pathophysiologic processes of stroke.
Keywords:
hemorrhage;
inflammatory biomarkers;
acute ischemic;
circulating inflammatory;
stroke;
ischemic stroke
Journal Title: Aging and Disease
Year Published: 2023
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Journal Title: Aging and Disease
Year Published: 2023
Link to full text (if available)
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recommendations!