LAUSR

Synovial sarcoma is a rare disease, with patient characteristics and survival data mostly derived from national databases. The authors investigated the patient population of synovial sarcoma at a single institution to determine whether there were differences in the regional patient population from national averages. Survival outcomes related to patient demographics were additionally investigated. Objectives The purpose of this study was to investigate the patient population and outcomes of synovial sarcoma at a single institution. Methods A retrospective review of the medical records of 28 patients with synovial sarcoma diagnosed from 1992 to 2017 was performed. Demographics, staging, disease location, treatment, and response to treatment were reviewed. Results Individuals with larger tumors at the time of presentation had an increased risk of death. An additional factor associated with poor prognosis in synovial sarcoma was increasing patient age. The patient population had a higher rate of nonextremity disease and lower overall survival when compared with national averages. Conclusions Nonextremity disease and large size of tumor at presentation may have contributed to the disparity in institutional outcomes from the national averages. The advanced presentation of synovial sarcoma remains a significant challenge in improving patient survival.