cuses on a few key features. First, patients with BrP have a reversible underlying condition, such as adrenal insufficiency, hypokalemia, or myocardial ischemia, that elicits or induces the Brugada ECG… Click to show full abstract
cuses on a few key features. First, patients with BrP have a reversible underlying condition, such as adrenal insufficiency, hypokalemia, or myocardial ischemia, that elicits or induces the Brugada ECG pattern. Once this underlying condition resolves, there is prompt normalization of the ECG. Second, patients with BrP have a low clinical pretest probability of true congenital BrS as opposed to a high clinical pretest probability in patients with BrS, who have a history of VF, polymorphic VT, nonvagal syncope, and a family history of sudden cardiac. Third, patients with BrP have a negative provocative challenge with a sodium channel blocker, whereas those with true congenital BrS have a positive provocative challenge. Therefore, ECG alone cannot be used as a diagnostic tool. Implantation of an implantable cardioverter defibrillation in an asymptomatic patient without a spontaneous type 1 Brugada electrocardiographic pattern has no benefit.
               
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