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The impact of cardiac loading on a novel metric of left ventricular diastolic function in healthy middle‐aged adults: Systolic–diastolic coupling

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Left ventricular (LV) restoring forces are primed by ventricular deformation during systole and contribute to cardiac relaxation and early diastolic suction. Systolic–diastolic coupling, the relationship between systolic contraction and diastolic… Click to show full abstract

Left ventricular (LV) restoring forces are primed by ventricular deformation during systole and contribute to cardiac relaxation and early diastolic suction. Systolic–diastolic coupling, the relationship between systolic contraction and diastolic recoil, is a novel marker of restoring forces, but the effect of left atrial pressure (LAP) is unknown. We tested preliminary methods of systolic–diastolic coupling comparing mitral annular velocities versus excursion distances and hypothesized a recoil/contraction distance ratio would remain unaffected across varying LAP, providing a surrogate for quantifying LV restoring forces.

Keywords: systolic diastolic; restoring forces; left ventricular; novel; diastolic coupling; impact cardiac

Journal Title: Physiological Reports
Year Published: 2021

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