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Abstract Objectives The aim of this study was to recognize the efficacy and safety of curcumin ointment on patients with knee osteoarthritis (OA) compare to diclofenac as standard medication. Methods… Click to show full abstract
Abstract Objectives The aim of this study was to recognize the efficacy and safety of curcumin ointment on patients with knee osteoarthritis (OA) compare to diclofenac as standard medication. Methods The topical effects of curcumin (10%) and diclofenac (1%) ointments were assessed through the visual analog scale (VAS) and Western Ontario and McMaster Universities Arthritis (WOMAC) index after three times a day administration for two weeks in 60 patients. Results Desirable effects compared to the pre-treatment period were observed after two weeks of continuous treatment. Based on our results, VAS and WOMAC index were altered after treatment significantly (p<0.0001). Conclusions Two-week use of curcumin ointment could ameliorate the pain, stiffness and function disability in patients with OA.
Journal Title: Journal of Basic and Clinical Physiology and Pharmacology
Year Published: 2022
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