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Anxiolytic effects of vestibular stimulation: an update

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Abstract The vestibular system inhibits both HPA and SAM axis and contributes to the management of anxiety. Both direct and indirect pathways exist in the inhibition of the HPA and… Click to show full abstract

Abstract The vestibular system inhibits both HPA and SAM axis and contributes to the management of anxiety. Both direct and indirect pathways exist in the inhibition of the HPA and SAM axis. In this review article, the authors describe various pathways through which the vestibular system can regulate the HPA and SAM axis activity. Lastly, the authors highlight the need of starting translational research work in this field. Rocking is soothing and this is a universal fact that babies in the swing will calm down and sleep. These soothing effects of vestibular stimulation may be due to the inhibition of cortical and subcortical structures. Vestibular stimulation may be able to manage anxiety through its connections with multiple brain areas. There is a need to undertake translational research in this area to establish strong scientific evidence and recommend implementation of the vestibular stimulation in the management of anxiety.

Keywords: vestibular stimulation; sam axis; hpa sam; effects vestibular; anxiolytic effects; stimulation

Journal Title: Journal of Basic and Clinical Physiology and Pharmacology
Year Published: 2023

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