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Simple naturally occurring β-carboline alkaloids – role in sustainable theranostics

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Abstract This review is a brief treatise on some simple β-carboline alkaloids that are abundantly available in plants, animals and foodstuff. These alkaloids are well known for their pharmacological action… Click to show full abstract

Abstract This review is a brief treatise on some simple β-carboline alkaloids that are abundantly available in plants, animals and foodstuff. These alkaloids are well known for their pharmacological action as well as their allelopathic behaviour. The focus of this review is on sustainable use of naturally occurring compounds in safeguarding human health and protecting our environment at large i.e. the prospective applications of these molecules for Sustainable Theranostics. The review commences with an initial introduction to the β-carboline alkaloids, followed by an outlay of their geographical distribution and natural abundance, then the basic structure and building units of the simplest β-carboline alkaloids have been mentioned. This is followed by a discussion on the important methods of extraction from natural sources both plants and animals. Then the foundation for the use of these alkaloids in Sustainable Theranostics has been built by discussing their interesting photophysics, interactions with important biological molecules and an extensive survey of their therapeutic potential and allelopathic behaviour. Finally the review ends with a silver lining mentioning the future prospective applications of these alkaloids with special relevance to sustainability issues.

Keywords: simple naturally; carboline alkaloids; sustainable theranostics; alkaloids role; occurring carboline; naturally occurring

Journal Title: Physical Sciences Reviews
Year Published: 2022

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