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METHODOLOGY FOR THE ENDOCRINOLOGIST: Basic aspects of confounding adjustment

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The results of observational studies of causal effects are potentially biased due to confounding. Various methods have been proposed to control for confounding in observational studies. Eight basic aspects of… Click to show full abstract

The results of observational studies of causal effects are potentially biased due to confounding. Various methods have been proposed to control for confounding in observational studies. Eight basic aspects of confounding adjustment are described, with a focus on correction for confounding through covariate adjustment using regression analysis. These aspects should be considered when planning an observational study of causal effects or when assessing the validity of the results of such a study.

Keywords: methodology; methodology endocrinologist; basic aspects; adjustment; aspects confounding; confounding adjustment

Journal Title: European Journal of Endocrinology
Year Published: 2020

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