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Neonatal Hemophagocytic Lymphohistiocytosis.

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Hemophagocytic lymphohistiocytosis (HLH) is extremely rare in the neonatal period. The incidence of neonatal HLH is not confirmed and may range from 1 in 50,000 to 150,000. The incidence varies… Click to show full abstract

Hemophagocytic lymphohistiocytosis (HLH) is extremely rare in the neonatal period. The incidence of neonatal HLH is not confirmed and may range from 1 in 50,000 to 150,000. The incidence varies based on ethnicity, particularly in populations in which consanguinity is common. HLH is associated with a high fatality rate and poor prognosis, making it important to recognize and diagnose it early. This review will concentrate primarily on the diagnosis and management of neonatal HLH.

Keywords: neonatal hemophagocytic; hlh; lymphohistiocytosis; hemophagocytic lymphohistiocytosis

Journal Title: NeoReviews
Year Published: 2019

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