LAUSR

A male neonate born at 24 2/7 weeks’ gestation is transferred to our facility at 81 days of age to receive bilateral diode laser photocoagulation therapy for high-risk retinopathy of prematurity. The infant is requiring a high amount of ventilator support secondary to diffuse, persistent pulmonary interstitial emphysema and bronchopulmonary dysplasia (BPD). The infant’s chest radiograph on admission to our facility is shown in Fig 1. Figure 1. Chest radiograph demonstrates a lobular hyperlucent lesion overlying the superior mediastinum and right medial thorax as well as diffuse coarsened lung markings consistent with chronic lung disease of prematurity. At the time, this lucent lesion was suspected to be a pneumatocele. ### Prenatal and Birth Histories ### Summary of Initial Hospital Course In the NICU, the infant required 2 additional doses of surfactant at 16 and 24 hours of age with high ventilator settings. In the first few months of age, he was switched between high-frequency oscillatory ventilation and conventional ventilation multiple times because of intermittent periods of inadequate ventilation and oxygenation. On the 6th day of age, he required antibiotic therapy for methicillin-sensitive Staphylococcus …