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Background: The highest combined rates of traumatic brain injury (TBI) related morbidity and mortality in the US occur in young children and adolescents. At the neurophysiological level, damages resulting from… Click to show full abstract
Background: The highest combined rates of traumatic brain injury (TBI) related morbidity and mortality in the US occur in young children and adolescents. At the neurophysiological level, damages resulting from forces generated from TBI induce biochemical changes that can be detected in body fluids. Elevated levels of S100B, a calcium binding protein, glial fibrillary acidic protein (GFAP), and neuron specific enolase (NSE) levels in CSF and serum, has been shown to correlate with neuro-radiological findings and Glasgow Coma Scores …
Journal Title: Pediatrics
Year Published: 2018
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