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To assess the impact of Sepsis Risk Calculator (SRC) in safely reducing antibiotic usage and lab tests in infants evaluated for early onset sepsis (EOS) in high risk population

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Background: Infants at risk for early onset sepsis (EOS) are evaluated based on current CDC/AAP guidelines (newborn nursery protocol). However, many well-appearing infants receive unnecessary empiric antibiotics despite extremely low… Click to show full abstract

Background: Infants at risk for early onset sepsis (EOS) are evaluated based on current CDC/AAP guidelines (newborn nursery protocol). However, many well-appearing infants receive unnecessary empiric antibiotics despite extremely low incidence of EOS. Quantitative risk-based prediction models such as Kaiser Permanente's Sepsis Risk Calculator (SRC)®, is an effort to minimize antibiotic exposure in this cohort. It is not certain however,that SRC will function equally well among high-risk population of infants whose mothers have a high rate of limited to no prenatal care (PNC). Objective: To assess the rate of antibiotic …

Keywords: sepsis; sepsis eos; onset sepsis; early onset; risk; sepsis risk

Journal Title: Pediatrics
Year Published: 2019

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