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Should Recommendations About Starting Inhaled Corticosteroid Treatment of Mild Asthma Be Based on Symptom Frequency: A Post-hoc Efficacy Analysis of the START Study

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HK Reddel, WW Busse, S Pedersen. Lancet. 2017;389(10065):157–166 The 3-year Steroid Treatment as Regular Therapy (START) study evaluated the symptom-based cutoff of >2 days per week for starting daily inhaled… Click to show full abstract

HK Reddel, WW Busse, S Pedersen. Lancet. 2017;389(10065):157–166 The 3-year Steroid Treatment as Regular Therapy (START) study evaluated the symptom-based cutoff of >2 days per week for starting daily inhaled steroid therapy for management of mild asthma. Participants ( N = 7138, ages 4–66 years) were from 32 countries, had mild asthma diagnosed within the past 2 years, and no previous regular corticosteroid therapy. This post-hoc analysis of a randomized control trial comparing once-daily inhaled …

Keywords: start study; mild asthma; treatment; post hoc

Journal Title: Pediatrics
Year Published: 2017

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