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Enterovirus and Parechovirus Coinfection in a Sudden Unexpected Infant Death

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In this report, we question the potential role of viral infections in the pathogenesis of sudden infant death and highlight the need of extensive virological investigations Viruses are suspected to… Click to show full abstract

In this report, we question the potential role of viral infections in the pathogenesis of sudden infant death and highlight the need of extensive virological investigations Viruses are suspected to play a role in the multifactorial pathogenesis of sudden infant death. We described a sudden and unexpected death in a 5-month-old boy, with detection of both enterovirus and parechovirus RNA in the blood. This is the first report of a dual viraemia of enterovirus and parechovirus and its potential association with a sudden unexpected infant death. Extensive sampling and testing especially using molecular methods currently available is needed to better understanding the “hypothetical” link between viral infections and sudden infant death.

Keywords: death; infant death; enterovirus parechovirus; unexpected infant; sudden unexpected

Journal Title: Pediatrics
Year Published: 2020

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