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Seropositivity for Chagas disease in blood donors from the state of Alagoas, Northeastern Brazil: an 11-year time series study

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Abstract INTRODUCTION Chagas disease can be transmitted by blood transfusion. Herein, we assessed the seropositivity for Chagas disease in blood donors from Alagoas, during 2010-2020. METHODS Data were requested from… Click to show full abstract

Abstract INTRODUCTION Chagas disease can be transmitted by blood transfusion. Herein, we assessed the seropositivity for Chagas disease in blood donors from Alagoas, during 2010-2020. METHODS Data were requested from the Alagoas blood center. Time trend analysis was performed using a joinpoint regression model. RESULTS Seropositivity rate during the study period was 0.35%, which decreased from 2014 to 2020, (annual percentage change, APC = -29.38; p-value <0.05), while the total number of tests performed remained stable (APC = 6.5). CONCLUSIONS Despite the drop in the seropositivity for Chagas infection in donors, it is imperative to maintain the screening of donors for the epidemiological control.

Keywords: seropositivity chagas; chagas disease; seropositivity; disease blood; blood

Journal Title: Revista da Sociedade Brasileira de Medicina Tropical
Year Published: 2021

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