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Involvement of bone in disseminated paracoccidioidomycosis

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FIGURE 1: (A): Patient with subacute disseminated form of paracoccidioidomycosis exhibiting multiple umbilicated skin-colored papules on the face. (B): Coronal multiplanar reformatted computed tomography of the anterior chest wall demonstrating… Click to show full abstract

FIGURE 1: (A): Patient with subacute disseminated form of paracoccidioidomycosis exhibiting multiple umbilicated skin-colored papules on the face. (B): Coronal multiplanar reformatted computed tomography of the anterior chest wall demonstrating the presence of multiple osteolytic lesions with cortical rupture of the sternal body, manubrium, and both clavicles. (C): A photomicrograph showing the thick birefringent cell wall of the fungus and the typical pattern of multiple budding around the mother cell, which is a characteristic feature of Paracoccidioides brasiliensis infection. An 18-year-old male patient previously healthy and immunocompetent presented with a 6-months history of cough, sputum production, malaise, and weakness. The patient had fever, diffuse lymph node enlargement, multiple cutaneous lesions, bone pain, and a purulent collection of on the thoracic wall adjacent to the left clavicle. He reported a weight loss of about 10 kg in just one month.

Keywords: paracoccidioidomycosis; bone disseminated; involvement bone; wall; disseminated paracoccidioidomycosis; patient

Journal Title: Revista da Sociedade Brasileira de Medicina Tropical
Year Published: 2021

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