HIGHLIGHTS Flavonoids potentially target GyrB. Screened flavonoids have good bioavailability and no toxicity. Flavonoids could preferentially interact with GyrB and some of them exhibit higher binding affinity towards GyrB than… Click to show full abstract
HIGHLIGHTS Flavonoids potentially target GyrB. Screened flavonoids have good bioavailability and no toxicity. Flavonoids could preferentially interact with GyrB and some of them exhibit higher binding affinity towards GyrB than novobiocin.
               
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