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In Silico Screening of DNA Gyrase B Potent Flavonoids for the Treatment of Clostridium difficile Infection from PhytoHub Database

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HIGHLIGHTS Flavonoids potentially target GyrB. Screened flavonoids have good bioavailability and no toxicity. Flavonoids could preferentially interact with GyrB and some of them exhibit higher binding affinity towards GyrB than… Click to show full abstract

HIGHLIGHTS Flavonoids potentially target GyrB. Screened flavonoids have good bioavailability and no toxicity. Flavonoids could preferentially interact with GyrB and some of them exhibit higher binding affinity towards GyrB than novobiocin.

Keywords: dna gyrase; potent flavonoids; gyrase potent; screening dna; silico screening; flavonoids treatment

Journal Title: Brazilian Archives of Biology and Technology
Year Published: 2021

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