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FIgure 2: Resolved erythema and secretion on the vulva, after treatment with zinc How to cite this article: Jiang S, Zhang Y, Zou X. Condyloma acuminata at urethral orifice complicated with hemophilia A. An Bras Dermatol. 2017;92(2):289-90. cause ulcer, bleeding, and damage to surrounding normal tissues, the urethral orifice would bleed during the treatment due to the deficiency of coagulant factor VIII, and his wound would be difficult to heal. Therefore, we applied 5-Aminolevulinic Acid Photodynamic Therapy to treat the condyloma acuminata at his urethral orifice, with no ulcer, bleeding, or infection observed during the treatment. During the 6-month follow-up examination, no recurrence or scar was found; the skin was smooth; and the condyloma acuminata lesion was totally removed. (Figure 2A and 2B). q