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Hypolipidemic and antioxidant effects of the juice and water seed extracts of two pomegranate species in high-cholesterol diet fed rats

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Cardiovascular disorders (CVDs) remain the leading cause of death worldwide, with very high incidence and mortality rates (Ashoor et al., 2019). Oxidative stress is known to be a key player… Click to show full abstract

Cardiovascular disorders (CVDs) remain the leading cause of death worldwide, with very high incidence and mortality rates (Ashoor et al., 2019). Oxidative stress is known to be a key player in the development of coronary heart disease and has been well described as the mechanism driving a range of health conditions, such as hypertension, dyslipidemia, metabolic syndrome, diabetes mellitus, and obesity (Pignatelli et al., 2018). Against this background, it is well established that the impairments of several pro-oxidant and antioxidant enzymes or mediators including nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, myeloperoxidase, glutathione reductase (GSH), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) are the major mechanisms behind initiation of the oxidative stress response in CVDs (Pignatelli et al., 2018).

Keywords: seed; hypolipidemic antioxidant; effects juice; antioxidant effects; water seed; juice water

Journal Title: Food Science and Technology International
Year Published: 2020

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