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TREATMENT OF SUSPECTED EXERTIONAL MYOPATHY USING DANTROLENE IN A COYOTE (CANIS LATRANS)

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Abstract:  A 3-yr-old spayed female coyote (Canis latrans) developed clinical signs of exertional myopathy after fighting with a conspecific. A diagnosis of exertional myopathy was made based on physical examination… Click to show full abstract

Abstract:  A 3-yr-old spayed female coyote (Canis latrans) developed clinical signs of exertional myopathy after fighting with a conspecific. A diagnosis of exertional myopathy was made based on physical examination findings, probable myoglobinuria, and elevations in serum creatinine kinase activity, alanine aminotransferase activity, and potassium concentration. Dantrolene, a hydantoin analog, as well as supportive and symptomatic therapies, was used to successfully treat exertional myopathy. This is the first reported use of dantrolene in wildlife or zoo animals.

Keywords: coyote canis; canis latrans; exertional myopathy; myopathy

Journal Title: Journal of Zoo and Wildlife Medicine
Year Published: 2018

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