LAUSR

Rosai-Dorfman disease (RDD) was originally described as a rare pseudolymphomatous disorder, characterised by persistent massive lymphadenopathy and caused by increased numbers of macrophages within lymph node sinuses [1, 2]. These macrophages are often large and exhibit abnormal behaviour, taking intact cells, such as lymphocytes, erythrocytes, and plasma cells, into the cytoplasm, as a phenomenon known as emperipolesis. Population sites of these abnormal macrophages are not confined to lymph node [...]