Mixed connective tissue disease (MCTD) is a rare connective tissue disease with an autoimmune background. Clinically, it is characterised by manifestations shared with other connective tissue diseases; systemic lupus erythematosus… Click to show full abstract
Mixed connective tissue disease (MCTD) is a rare connective tissue disease with an autoimmune background. Clinically, it is characterised by manifestations shared with other connective tissue diseases; systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and polymyositis/dermatomyositis [1, 2]. High titres of distinct serum autoantibodies to the U1 small nuclear ribonucleoprotein (RNP) are characteristic of MCTD. Several skin manifestations of MCTD are known, including Raynaud's phenomenon, [...]
Journal Title: European Journal of Dermatology
Year Published: 2017
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