Linear IgA bullous dermatosis (LABD) is a rare acquired autoimmune bullous disease. An adult and childhood variant are recognized. A two-year-old boy was admitted to the emergency room of our… Click to show full abstract
Linear IgA bullous dermatosis (LABD) is a rare acquired autoimmune bullous disease. An adult and childhood variant are recognized. A two-year-old boy was admitted to the emergency room of our university with a generalized blistering skin eruption, involving over 30% of body surface. Clinical manifestations had started 10 days before, following low-dose aspirin administration (100-mg tablet/day for two consecutive days) due to his mother’s decision to treat a cold, without consultation with a doctor. Initial diagnosis by his practitioner was chickenpox. Treatment with acyclovir was established with no remission of disease. On admission, physical examination revealed a widespread eruption of grouped tense blisters, localized on the face, trunk and, symmetrically, on the arms and legs. Some vesicles were present at the edge of annular or polycyclic lesions, displaying the classic “string of beads” sign (figure 1A, B). In particular, oral mucosa, eyes, and nails were spared. General condition was good; the child was
               
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