LAUSR

Figure 1. A-C) Clinical appearance of skin lesions: wellcircumscribed, round-to-oval areas of oedematous targetoid erythema, <6 cm in diameter, with dusky centres scattered on the trunk. On the upper left chest, the long axis of a lesion follows Langer’s lines, mimicking a V-shaped collar (black arrow), while those on the anterior axilla follow Langer’s lines running laterally (white arrows), resulting in the opposite direction of each long axis (A). Lesions on the abdomen follow Langer’s lines running transversely (B). Lesions on the middle back follow a Christmas tree pattern (C). D, E) Histopathological findings for an area of skin showing targetoid erythema on the trunk showing hydropic degeneration of the basal layer in the epidermis (haematoxylin and eosin; original magnification: ×200) (D) and perivascular inflammatory infiltrate comprising lymphocytes and some eosinophils in the upper dermis (haematoxylin and eosin; original magnification: ×200) (E).