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ALK-positive atypical Spitz tumour with conspicuous rosette-like structures

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EJD, vol. 31, n◦ 2, March-April 2021 in this process, although gene analysis was not performed in the present case. The present patient and the previously reported patient [3] were… Click to show full abstract

EJD, vol. 31, n◦ 2, March-April 2021 in this process, although gene analysis was not performed in the present case. The present patient and the previously reported patient [3] were followed for more than four and six years, respectively, after the development of subcutaneous metastasis. Cutaneous/subcutaneous metastases of GIST does not always predict poor prognosis. In conclusion, subcutaneous nodules in patients with a history of GIST should be biopsied immediately. If a spindle cell tumour such as a leiomyoma, leiomyosarcoma or dermatofibrosarcoma protuberans is suspected, subcutaneous metastasis of GIST should be considered as a differential diagnosis, even many years after the primary GIST resection.

Keywords: positive atypical; atypical spitz; tumour conspicuous; alk positive; spitz tumour; conspicuous rosette

Journal Title: European Journal of Dermatology
Year Published: 2021

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