LAUSR

Chondroid syringoma is a rare tumour which preferably occurs on the head and neck and seems to be more frequent in men, with, however, malignant features more frequently described in women [1]. In the most common cases, the tumour is characterized by a solitary, firm papule or nodule. It grows slowly over several months and is generally asymptomatic [2]. It is often mistaken with common benign or malignant, cutaneous lesions, such as epidermoid cysts, pilar cyst, basal cell carcinoma or other adnexal tumours. Histologically, chondroid syringoma features a well-demarcated tumour with epithelial components forming nests and glandular structures surrounded by a chondroid and/or fibromyxoid stroma. Most of the cases feature apocrine differentiation [3]. The standard treatment is surgery [4] to avoid growth, ulceration and necrosis [2]. After excision, local recurrence rarely occurs but has been reported in up to 20% of chondroid syringoma cases with malignant features and mostly when surgical removal is incomplete [5]. The lack of clinical and dermoscopic specific features may result in misdiagnosis with a risk of delayed diagnosis and tissue-damaging surgery.