LAUSR

Toxoplasmosis is an important disease, which is caused by obligate intracellular parasite Toxoplasma gondii. Maternal infection with toxoplasmosis during pregnancy is frequently stimulates the immune response that may cause the fetus to be lost or deformed. A case control study were conducted in Al-Nassiriya province, southern Iraq to measure the interleukin-6 and interleukin-1-β levels. One hundred and twenty seven recurrent aborted women suspected with toxoplasmosis attending to Bent Al-Huda Maternity and Child Hospital for the period from March 2020 to March 2021, and compared to (20) healthy women as a control group. The ages ranged between 16-42 years, 5 ml of blood samples were collected for serum detection positivity of latex agglutination test, Enzyme Linked immune sorbent assay (interleukin-6 and interleukin-1-β). The distribution analysis showed that the highest toxoplasmosis among aborted women compared to healthy control group, the infection rate were (39.37%). Higher percentages of toxoplasmosis (82.35%) was found within the age group (15-25) years. In addition, the results showed a high positive of toxoplasmosis in 43 cases out of 50 cases by latex agglutination test. Also, the result indicated increasing levels of IL-6 and IL-1-β in patients' sera (24.69, 14.21) respectively, compared to healthy women.