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Inappropriate Laughter in a Patient with Hypothalamic Hamartoma

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A two-year and seven-month-old boy presented to the Emergency Department at Sultan Qaboos University Hospital, Muscat, Oman, in 2019, with a two-day history of uprolling of eyeballs, unresponsiveness and drooling… Click to show full abstract

A two-year and seven-month-old boy presented to the Emergency Department at Sultan Qaboos University Hospital, Muscat, Oman, in 2019, with a two-day history of uprolling of eyeballs, unresponsiveness and drooling of saliva lasting for seconds. There was no abnormal limb movement or loss of tone. The episodes were followed by a postictal state that lasted 30 minutes. There were no triggers for the episodes, such as fever or intercurrent illness. The patient was born at term gestation to a consanguineous marriage. Antenatal, birth and family history were unremarkable. His developmental milestones were appropriate for his age and his immunisation was up-to-date. A sleep electroencephalogram (EEG) showed abnormal interictal generalised epileptiform discharges with no associated clinical accompaniment. There were bilateral occipital epileptiform discharges with slowing over the left

Keywords: inappropriate laughter; patient hypothalamic; laughter patient; hypothalamic hamartoma

Journal Title: Sultan Qaboos University Medical Journal
Year Published: 2020

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