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The 4 mg drospirenone preparation became available in Australia in October 2021 after we wrote the article.1 For contraceptives containing drospirenone, a 2012 Cochrane meta-analysis tentatively described improvement in women… Click to show full abstract
The 4 mg drospirenone preparation became available in Australia in October 2021 after we wrote the article.1 For contraceptives containing drospirenone, a 2012 Cochrane meta-analysis tentatively described improvement in women with premenstrual dysphoric disorder, however there was a large placebo effect.2 Our clinical experience with the 20 microgram ethinylestradiol/3 mg drospirenone preparation in women with premenstrual dysphoric disorder and (commonly) a trauma history is that the lower dose ethinylestradiol, compared to many other preparations, did not improve premenstrual dysphoric disorder as well as the combination of estradiol and nomegestrol.3
Journal Title: Australian Prescriber
Year Published: 2022
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