LAUSR

Background: Rotaviruses cause acute diarrhoea, mostly in young puppies. Rotavirus associated gastroenteritis in dog is of great concern not only because of their high morbidity and mortality, but became of the reason that, they act as potential source of zoonotic infection and inter-species transmission. There is no report on rotavirus infection in dog from Assam. Therefore, there is a need to study the haemato-biochemical alterations in rotavirus infected dogs while treating such type of clinical cases. Methods: A total of 157 faecal and blood samples were collected from the dogs affected with gastroenteritis, registered at Veterinary Clinical Complex, Khanapara, Assam during November, 2020 to April, 2021. Diagnosis of rotavirus was done by RNA-PAGE and RT-PCR. Haematological study of the canine rotavirus (CRV) infected dogs were carried out with automated haematological cell counter and biochemical analysis was done with semi-automated biochemistry analyser using commercial kit. Result: Out of 157 samples, 8 samples were found positive for canine rotavirus by RNA-PAGE and 17 samples by RT-PCR. Haemato-biochemical alterations in canine rotavirus infected dogs revealed significant increase in Hb, PCV, TEC, monocyte, lymphocyte, AST, ALT, BUN and creatinine while significant decrease in TLC, neutrophil, total protein, serum sodium, potassium and chloride.