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11C-Choline positive but 18F-FDG negative pancreatic metastasis from renal cell carcinoma on PET

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ABSTRACT Choline is a new PET tracer, which uptake may occur via a choline-specific transporter protein and be accelerated during the proliferation of tumor cells. We report a 61-year-old woman… Click to show full abstract

ABSTRACT Choline is a new PET tracer, which uptake may occur via a choline-specific transporter protein and be accelerated during the proliferation of tumor cells. We report a 61-year-old woman with a metastatic pancreatic tumor from renal cell carcinoma, measuring 35×40 mm. PET scans demonstrated accumulation of 11C-choline in the metastatic pancreatic tumor, but no accumulation of 18F-FDG. Choline PET/CT may play a useful and complementary imaging modality, especially when FDG-PET/CT does not show expected findings or when the evaluation of tumor viability is needed, in patients with renal cell carcinoma.

Keywords: choline; renal cell; cell carcinoma; 11c choline

Journal Title: Nagoya Journal of Medical Science
Year Published: 2017

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