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Comparison of Al 18F-NOTA-FAPI-04 and 18F-FDG in recurrent esophageal cancer after surgery.

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Recently, radionuclide labelling fibroblast activating protein inhibitors (FAPI) is regarded as the most promising imaging tracer forvarious tumours. Here we present the imaging finding of aluminium-[18F] fluoride (Al18F)-labelled 1,4,7-triazacyclononane-N,N',N"-triacetic acid… Click to show full abstract

Recently, radionuclide labelling fibroblast activating protein inhibitors (FAPI) is regarded as the most promising imaging tracer forvarious tumours. Here we present the imaging finding of aluminium-[18F] fluoride (Al18F)-labelled 1,4,7-triazacyclononane-N,N',N"-triacetic acid (Al18F-NOTA-FAPI-04) and fluorine-18-fluorodeoxyglucose (18F-FDG) in postoperative recurrence esophageal cancer. The results presented that imaging with Al18F-NOTA-FAPI-04 showed significant improvement in detection of local recurrence and distant metastasis with higher maximum standardized uptake value (SUVmax) in the lesions compared with 18F-FDG.

Keywords: 18f fdg; nota fapi; esophageal cancer

Journal Title: Hellenic journal of nuclear medicine
Year Published: 2023

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