OBJECTIVE to assess the prevalence of hypovitaminosis D in patients undergoing haemodialysis (HD) and to determine its relationship with nutritional status and quality of life (QoL). MATERIAL AND METHODS 120… Click to show full abstract
OBJECTIVE to assess the prevalence of hypovitaminosis D in patients undergoing haemodialysis (HD) and to determine its relationship with nutritional status and quality of life (QoL). MATERIAL AND METHODS 120 patients were included in the study. The Malnutrition-Inflammation Score (MIS) was used to detect nutritional risk. QoL was evaluated by Kidney Disease Quality of Life version 1.2 (KDQOL-SF). Patients were stratified into three groups according to their vitamin D status: sufficiency (≥ 30 ng/dl), insufficiency (29-10 ng/dl) and deficiency (< 10 ng/dl). RESULTS hypovitaminosis D was detected in 71 % of the patients studied. Multiple linear regression analysis showed that vitamin-D deficiency was the most significant predictor of low KDQOL-SF scores. It explained 21 % of the variance in the Kidney Disease Component Summary, 27 % of that in the Physical Component Summary, and 22 % of that in the Mental Component Summary. Multiple logistic regression analysis showed that only vitamin-D deficiency was significantly associated with malnutrition (OR, 14.6, p < 0.001). CONCLUSION HD patients frequently present with hypovitaminosis D. There is a significant correlation between vitamin-D deficiency, poorer nutritional status, and worse QoL in dialysed patients.
               
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