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Lymph node positive prostate cancer: the evolving role of adjuvant therapy

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For decades, lymph node metastasis (LNM) at the time of radical prostatectomy (RP) has been considered as a poor prognostic sign. Currently, the appropriate timing for androgen deprivation therapy (ADT)… Click to show full abstract

For decades, lymph node metastasis (LNM) at the time of radical prostatectomy (RP) has been considered as a poor prognostic sign. Currently, the appropriate timing for androgen deprivation therapy (ADT) remains controversial. Only one small prospective randomized study (ECOG 3886) has shown improved survival for immediate vs. delayed ADT in this select group of patients (1).

Keywords: node positive; prostate cancer; therapy; lymph node; positive prostate

Journal Title: Translational cancer research
Year Published: 2018

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