LAUSR

BACKGROUND Peritoneal dialysis (PD) uses the peritoneum as the dialysis membrane. PD is a simple operation for self-treatment at home, and has become the preferred option for most patients with chronic renal failure (CRF). This study aimed to explore the effect of a closed-loop health management (CLHM) system based on an Internet platform in patients with PD. METHODS A total of 102 patients with PD who were admitted to Xuzhou Central Hospital from May 2019 to May 2020 were selected and randomly divided into two groups (n=51). The control group received routine care, and in the observation group a CLHM based on an Internet platform was introduced. The incidence of complications and changes in disease knowledge, nutritional status, quality of life (QOL) before and after the intervention were compared between groups. RESULTS The incidences of peritonitis, tunnel entrance infection, poor drainage, and hypokalemia in the observation group were lower than in the control group (P<0.05). The disease-related knowledge mastery scores of the observation group were higher than those in the control group after 3 months of intervention (P<0.05). Malnutrition-inflammation score (MIS) and serum creatinine (SCr) in the observation group were lower than in the control group after 3 months of intervention (P<0.05), and the body mass index (BMI), albumin (ALB), and hemoglobin (Hb) of the observation group were higher than those of the control group (P<0.05). The QOL scores of the observation group were higher than those of the control group after 3 months of intervention (P<0.05). CONCLUSIONS The application of a CLHM system based on an Internet platform to patients with PD could effectively reduce complications, and improve patients' knowledge of disease, nutritional status and QOL. TRIAL REGISTRATION ClinicalTrials.gov Identifier: ChiCTR2100046122.