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Pancreatic cancer is projected to become the second leading cause of cancer death in the United States by 2030. Deleterious germline mutations can contribute to pancreatic cancer susceptibility. Herein we… Click to show full abstract
Pancreatic cancer is projected to become the second leading cause of cancer death in the United States by 2030. Deleterious germline mutations can contribute to pancreatic cancer susceptibility. Herein we report a case of a patient with metastatic pancreatic adenocarcinoma to the lung and liver who was found to have a deleterious germline mutation in RAD51C who had a remarkable response to chemotherapy with FOLFIRINOX, a platinum-containing regimen.
Keywords:
response;
rad51c;
pancreatic cancer;
cancer;
germline;
mutation
Journal Title: Journal of gastrointestinal oncology
Year Published: 2018
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Journal Title: Journal of gastrointestinal oncology
Year Published: 2018
Link to full text (if available)
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recommendations!