The exploration of cancer prognostic factor has received increasing attention in recent years. Traditional indicators such as tumor-node-metastasis system, histological subtype and carcinoembryonic antigen (CEA) have been recognized as prognostic… Click to show full abstract
The exploration of cancer prognostic factor has received increasing attention in recent years. Traditional indicators such as tumor-node-metastasis system, histological subtype and carcinoembryonic antigen (CEA) have been recognized as prognostic indicators. However, invasiveness and high cost of these factors restrict the widespread use in clinic, particularly in economically underdeveloped basic health units. Therefore, economic, simple and effective biomarkers are warranted to manage and improve prognosis of cancer individuals.
               
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