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Simultaneous acute Marchiafava-Bignami disease and posterior reversible encephalopathy syndrome: a case almost misdiagnosed.

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Marchiafava-Bignami disease (MBD) is a rare neurological disease, and is characterized by callosal lesions consisting of necrosis and demyelination. Posterior reversible encephalopathy syndrome (PRES) is a clinical syndrome, and refers… Click to show full abstract

Marchiafava-Bignami disease (MBD) is a rare neurological disease, and is characterized by callosal lesions consisting of necrosis and demyelination. Posterior reversible encephalopathy syndrome (PRES) is a clinical syndrome, and refers to a disorder with reversible subcortical vasogenic brain edema, predominantly involving the bilateral parieto-occipital regions. Never before had articles reported that the two diseases occurred simultaneously. We report a 49-year-old male alcoholic with both MBD and PRES who had a good prognosis after correct diagnosis and timely treatment.

Keywords: bignami disease; encephalopathy syndrome; posterior reversible; disease; reversible encephalopathy; marchiafava bignami

Journal Title: Quantitative imaging in medicine and surgery
Year Published: 2020

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