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The role of adipose stroma in prostate cancer aggressiveness.

Resistance of prostate cancer to treatment remains a challenge. Surgery, chemotherapy, and androgen deprivation therapy cure most patients with early-stage disease. However, metabolic reprogramming, androgen receptor bypass, and sustained immunotolerance… Click to show full abstract

Resistance of prostate cancer to treatment remains a challenge. Surgery, chemotherapy, and androgen deprivation therapy cure most patients with early-stage disease. However, metabolic reprogramming, androgen receptor bypass, and sustained immunotolerance results in treatment-refractory prostate cancer that progresses to metastatic and lethal stages.

Keywords: adipose stroma; prostate; stroma prostate; prostate cancer; role adipose

Journal Title: Translational andrology and urology
Year Published: 2019

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