Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with poor prognosis for afflicted patients. The incidence of ICC has increased over recent years, ICC accounts for 15–20% of all primary hepatobiliary… Click to show full abstract
Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with poor prognosis for afflicted patients. The incidence of ICC has increased over recent years, ICC accounts for 15–20% of all primary hepatobiliary malignancies (1-3). According to some studies, several proteins, e.g., carbohydrate antigen (CA) 19-9, can serve as biomarkers that can be used in the process of accurate prognosis prediction (4,5). Thus, further research to elucidate mechanisms related to the ICC progression is still Original Article
               
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