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Overexpression of SEZ6L2 predicts poor prognosis in patients with cholangiocarcinoma

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Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with poor prognosis for afflicted patients. The incidence of ICC has increased over recent years, ICC accounts for 15–20% of all primary hepatobiliary… Click to show full abstract

Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with poor prognosis for afflicted patients. The incidence of ICC has increased over recent years, ICC accounts for 15–20% of all primary hepatobiliary malignancies (1-3). According to some studies, several proteins, e.g., carbohydrate antigen (CA) 19-9, can serve as biomarkers that can be used in the process of accurate prognosis prediction (4,5). Thus, further research to elucidate mechanisms related to the ICC progression is still Original Article

Keywords: poor prognosis; prognosis; predicts poor; sez6l2 predicts; overexpression sez6l2; prognosis patients

Journal Title: Translational cancer research
Year Published: 2020

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