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Department of Thoracic Medical Oncology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, Fuzhou 350014, China; Fujian Provincial Key Laboratory of Translation Cancer Medicine, Fuzhou 350014, China; Fujian Provincial Key Laboratory of Tumor Biotherapy, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, Fuzhou 350014, China; Department of Radiobiology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, Fuzhou 350014, China; Department of Molecular and Cellular Biology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA Contributions: (I) Conception and design: Z He, R Lin; (II) Administrative support: Y Su; (III) Provision of study materials or patients: F Gong, J Liao, Q Wang, Y Su, C Chen, J Lin, R Lin; (IV) Collection and assembly of data: F Gong, J Liao; (V) Data analysis and interpretation: Z He, J Liao; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. These authors contributed equally to this work. Correspondence to: Zhiyong He. Department of Thoracic Medical Oncology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, No. 420 Fuma Road, Fuzhou 350014, China. Email: [email protected]; Jinrong Liao. Department of Radiobiology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, No. 420 Fuma Road, Fuzhou 350014, China. Email: [email protected].