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Clinicopathological and prognostic implications of vessels encapsulate tumor clusters with PD-L1 in intrahepatic cholangiocarcinoma patients

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Intrahepatic cholangiocarcinoma (ICC) ranks second and accounts 10–15% in primary liver cancers (1). Although ICC has made great progress in molecular basis, diagnosis and treatment, its morbidity and mortality are… Click to show full abstract

Intrahepatic cholangiocarcinoma (ICC) ranks second and accounts 10–15% in primary liver cancers (1). Although ICC has made great progress in molecular basis, diagnosis and treatment, its morbidity and mortality are still steadily increasing worldwide (2). Currently, most ICC patients are diagnosed with advanced disease, as they are not eligible for complete surgical resection (3). Therefore, new models and biomarkers are urgently needed to stratify ICC patients based on their prognosis for better risk stratification and Original Article

Keywords: intrahepatic cholangiocarcinoma; implications vessels; cholangiocarcinoma; vessels encapsulate; prognostic implications; clinicopathological prognostic

Journal Title: Translational cancer research
Year Published: 2020

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