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Identifying therapeutic vulnerabilities in lung cancer: application of a chemistry-first approach.

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In the last three decades, 5-year relative survival rates for lung cancer improved slightly, from 14.3%, 15.5%, and 18.4% (1). One of the reasons for these dismal survival rates is… Click to show full abstract

In the last three decades, 5-year relative survival rates for lung cancer improved slightly, from 14.3%, 15.5%, and 18.4% (1). One of the reasons for these dismal survival rates is that most patients present with advanced-stage disease, a time during which systemic therapies are unlikely to be curative.

Keywords: identifying therapeutic; vulnerabilities lung; therapeutic vulnerabilities; chemistry; lung cancer

Journal Title: Translational lung cancer research
Year Published: 2018

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