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Extramedullary Hematopoiesis Adjacent to Vertebral Fracture in a Patient with Pernicious Anemia

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Case: A 68-year-old woman presented with a paraspinal mass of indeterminate imaging characteristics. Workup and computed tomography-guided Fine Needle Aspiration (FNA) aspiration revealed extramedullary hematopoiesis (EMH) adjacent to a prior… Click to show full abstract

Case: A 68-year-old woman presented with a paraspinal mass of indeterminate imaging characteristics. Workup and computed tomography-guided Fine Needle Aspiration (FNA) aspiration revealed extramedullary hematopoiesis (EMH) adjacent to a prior compression fracture in the setting of pernicious anemia. Conclusion: The combination of findings suggests a possible relationship of the compression fracture and the EMH because of traumatic extravasation of marrow contents, with the patient's underlying anemia possibly providing an underlying predisposition to EMH.

Keywords: hematopoiesis adjacent; pernicious anemia; fracture; extramedullary hematopoiesis

Journal Title: JBJS Case Connector
Year Published: 2023

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