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Prurigo Pigmentosa Successfully Treated with Oral Minocycline: A Case Report

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Purpose We aimed to report a case of prurigo pigmentosa (PP) with blisters. Patients and Methods A 21-year-old male patient presented to our hospital with erythema, papules, and blisters all… Click to show full abstract

Purpose We aimed to report a case of prurigo pigmentosa (PP) with blisters. Patients and Methods A 21-year-old male patient presented to our hospital with erythema, papules, and blisters all over the front chest and back. Densely distributed round and oval edematous erythema was noted on the neck, front chest, and back of the patient. Histopathologic examination of the skin lesions (blisters) on the chest revealed epidermal cell hyperkeratosis. He was diagnosed with PP and was treated with oral minocycline. Results After 1-week minocycline administration, the patient’s itching was relieved, and the blisters dried up. His skin lesions recurred following self-withdrawal from the medication; subsequently, the patient was administered oral minocycline treatment again. After 1-month continuous oral treatment, the drug was discontinued. No recurrence of symptoms was noted. Conclusion Oral minocycline is effective for the treatment of PP.

Keywords: prurigo pigmentosa; report; treated oral; case; oral minocycline; minocycline

Journal Title: Clinical, Cosmetic and Investigational Dermatology
Year Published: 2023

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