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Lithium-Associated Generalized Ostraceous Psoriasis Treated with Adalimumab: A Case Report

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Abstract Ostraceous psoriasis is a rare variant of psoriasis, characterized by severe hyperkeratotic lesions resembling an oyster shell. Adalimumab is a biological agent that antagonizes tumor necrosis factor (TNF) and… Click to show full abstract

Abstract Ostraceous psoriasis is a rare variant of psoriasis, characterized by severe hyperkeratotic lesions resembling an oyster shell. Adalimumab is a biological agent that antagonizes tumor necrosis factor (TNF) and is used clinically in plaque psoriasis. Some medications such as lithium carbonate (LC) may aggravate or trigger psoriasis. Here, we describe a case of generalized ostraceous psoriasis associated with lithium carbonate, whose lesions completely improved after discontinuing lithium carbonate and using adalimumab.

Keywords: case; generalized ostraceous; psoriasis; lithium carbonate; ostraceous psoriasis

Journal Title: Clinical, Cosmetic and Investigational Dermatology
Year Published: 2023

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