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We appreciate the authors publishing their research “Combined Silver Sulfadiazine Nanosuspension with Thermosensitive Hydrogel: An Effective Antibacterial Treatment for Wound Healing in an Animal Model” in International Journal of Nanomedicine:18,… Click to show full abstract
We appreciate the authors publishing their research “Combined Silver Sulfadiazine Nanosuspension with Thermosensitive Hydrogel: An Effective Antibacterial Treatment for Wound Healing in an Animal Model” in International Journal of Nanomedicine:18, 679–691. 1 This information is crucial to understand the effectiveness of nanosized silver sulfadiazine loaded in poloxamer thermosensitive hydrogel (NS/Gel) and its safety in vivo. Pseudomonas aeruginosa, Staphylococcus aureus , and methicillin-resistant S. aureus (MRSA) are the most common microbial strains found in patients with infected wounds. Metal nanoparticles (NPs) like zinc (Zn), silver (Ag), and gold (Au) have bacteriostatic/bactericidal activity including low in vivo toxicity and they are suggested wound dressings. 2 Previous study reported that the combination of silver sulfadiazine (AgSD) nanosuspensions and thermoresponsive hydrogel decreased cytotoxicity using the methyl thiazolyltetrazolium (
Journal Title: International Journal of Nanomedicine
Year Published: 2023
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