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Mitochondria are the key players in cell metabolism, calcium homeostasis, and reactive oxygen species (ROS) production. Mitochondrial genome alterations are reported to be associated with numerous human disorders affecting nearly… Click to show full abstract
Mitochondria are the key players in cell metabolism, calcium homeostasis, and reactive oxygen species (ROS) production. Mitochondrial genome alterations are reported to be associated with numerous human disorders affecting nearly all tissues. In this review, we discuss the available information on the involvement of mitochondrial DNA (mtDNA) mutations in cell dysfunction.
Keywords:
cellular functional;
genome variability;
effect cellular;
mitochondrial genome;
genome;
variability effect
Journal Title: Therapeutics and Clinical Risk Management
Year Published: 2018
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Journal Title: Therapeutics and Clinical Risk Management
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!