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Monoclonal B-cell Lymphocytosis Exacerbated by Prednisolone Therapy for Dermatomyositis

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Lymphoproliferative diseases have been associated with various autoimmune diseases. We experienced a case of non-chronic lymphocytic leukemia type monoclonal B-cell lymphocytosis (MBL) that was exacerbated by increasing prednisolone for dermatomyositis… Click to show full abstract

Lymphoproliferative diseases have been associated with various autoimmune diseases. We experienced a case of non-chronic lymphocytic leukemia type monoclonal B-cell lymphocytosis (MBL) that was exacerbated by increasing prednisolone for dermatomyositis and then improved by decreasing the dosage. Because MBL is difficult to diagnose, cases like ours may not be rare. These findings will facilitate our understanding of the mechanism underlying lymphoproliferative diseases and autoimmune diseases.

Keywords: monoclonal cell; cell lymphocytosis; prednisolone; dermatomyositis

Journal Title: Internal Medicine
Year Published: 2021

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